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Difference Between PVC And DEHP Free IV Set

infusion set

Polyvinyl chloride (PVC) infusion set

IV sets manufacturers use PVC-containing DEHP to produce infusion sets to achieve high strength, flexibility, transparency, easy sealing, good resistance to sterilization procedures, and comparatively low cost.

DEHP, an abbreviation for di(2- ethylhexyl) phthalate, is a manufactured chemical commonly added to plastics to make them flexible. Other names for this compound are dioctyl phthalate (DOP) and bis(2-ethylhexyl) phthalate (BEHP).

However, the expected chemical bonding between the DEHP and PVC does not occur. Consequently, the DEHP molecules easily detach themselves from the infusion set materials, brought about by leaching, and enter the systems of the patient together with the infusion fluid.

As previously established in some studies, DEHP has several toxic effects, such as damaging the infant’s genital system.

By itself, exposure to PVC causes several adverse health effects, and the addition of plasticizers makes them worse. These adverse health effects include the following:

  1. Hormonal imbalances
  2. Disruption in reproductive and developmental processes
  3. Several forms of allergies common in children
  4. Brain cancer
  5. Scleroderma (hardening of connective tissues)
  6. Malignant tumors.

DEHP Free IV set

Some IV set manufacturers ensure that patients receive fluid and drug infusions free from DEHP to protect them from possible toxicities. Thus, the IV set manufacturers to design the whole infusion line, including the drip chamber and the tubing, free from DEHP. The transparent PVC and transparent part of the drip chamber are parts of the IV set that are made of PVC. The other parts are made of ABS, PE, PP, etc.

The administration of two chemotherapy drugs, Taxol and Taxotere, causes and promotes the separation of DEHP from the infusion set. Thus, infusion sets used for cancer patients need to be free from DEHP throughout the IV fluid path.

Usually, we can know whether it’s DEHP or DEHP free IV set by looking for the label on the packing. It can help us identify products very well.

About Us

We, Liaoning KANGYI Medical Equipment, boasting three decades of specialized experience, are a seasoned manufacturer dedicated to producing syringes and IV tubing. Our factory has successfully undergone the rigorous scrutiny of a TUV audit, and we proudly hold a CE certificate in compliance with MDR 2017/745. Our lead time of a 40HC container is about 40 days. Click here to check our production process.

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